Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1896 | 1896-30623 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54M, L90M | L33F, G73GS | L10I, I62V, L63P, I64L, I66V, A71T, V77I, I93L, C95F |
| >1896-30623| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTIFEEMNLPGRWKPKIVGGIGGFMKVRQYDQVP LEVCGHKTISTVLIGPTPVNIIGRNLMTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, L74V, M184V | K219Q | K103N, Y181C | T39A, V60I, V118I, D123E, I135T, S162SG, T165TI, R211RK, F214L, H221Y, V245T |
| >1896-30623| codons 38-247 CAEMEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQGSMIKILEPFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTP DQKYQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |