Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1570 | 1570-30313 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70KR, L74I, M184V, T215F | K219Q | Y181C | A98G | T39A, V118I, K122E, K166R, V179I, G196S, I202V, Q207E, R211K, F214L, L228H, V245M |
| >1570-30313| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIIICQYVDDLYVGSDLEISQHRTKVEELREHLLKWGLFTP DQKHQKEPPFHWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | V11I, G73ST | L10I, I15V, L19P, K20I, R41K, L63P, H69K, K70R, A71V, I72LM, N83NS, I85IV |
| >1570-30313| codons 4-99 TLWQRPIITIKVGGQPIEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFVKVRQYDQIP IEICGKRVMTTVLVGPTPVSVVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |