Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2111 | 2111-30724 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | V11VI, G73S | L10I, I15IV, A22AV, E34EQ, R41K, I62V, L63P, A71V, I72L, V77I, I85V |
| >2111-30724| codons 4-99 TLWQRPIITIKVGGQLKEVLLDTGADDTVLQEMNLPGKWKPKMIGGIGGFVKVRQYDQVP IEICGHKVLSTVLIGPTPANIVGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, L74V, T215F | K219Q | Y181C, G190A | T39TA, K43E, K64H, T69N, K122E, Q174H, V179VI, Q207E, D218E, L228H, V245Q |
| >2111-30724| codons 38-247 CAELEEEGKISKIGPENPYNTPVFAIHKKNSNRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKHNPDIIICQYMDDLYVASDLEIGQHRTKIEELREHLLRWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |