Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1909 | 1909-30819 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, Y115F, M184V, T215F | K219E | K101E, Y181C, G190S | V108I | T69N, K122E, S162C, N175H, I178M, I195V, G196E, D218E, H221Y, L228R |
| >1909-30819| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTILDVGDAFFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQHPDMVICQYVDDLYVSSDLEVEQHRTKIEELRQHLLRWGFFTP EEKYQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V | L24I | L10IV, G16A, K20R, E35D, M36I, N37D, I62V, L63P, A71V, I72V, I85V, I93L |
| >1909-30819| codons 4-99 TLWQRPVVTIKIAGQLREALIDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVRQYDQVP IEICGHKVVGTVLVGPTPTNVVGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |