Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1160 | 1160-30508 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90M | L33F, Q58E | L10I, K20R, E34N, E35D, M36I, N37ND, P39PS, I62V, L63P, A71V, I93L |
| >1160-30508| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVFNDIDLSGRWKPKMIGGIGGFVKVREYDQVP IEICGHKVIGTVLVGPTPANVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | T39A, R83K, K122E, I178M, Q197L, T200TA, R211K |
| >1160-30508| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGLHRAKIEELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |