<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1763 1763-30424 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, V75T, M184V, L210W, T215Y K219D K103N, Y181C, G190A A98G T39A, K101Q, V118VI, K122E, I135L, T200A, E203K, Q207QE, K223Q, L228H  
>1763-30424| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHP
GGLQKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRAKIKELREHLWRWGFYTP
DDKHQQEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, I84V   T4S, L10V, T12M, I15V, L19V, K20R, M36I, L63T, A71V, I72T, T74E, I93L  
>1763-30424| codons 4-99
SLWQRPVVMIKVGGQVREALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVKVRQYDQIT
IEICGHKVTGEVLVGPTPANVIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006