Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1134 | 1134-30326 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54M, I84V, L90M | L10F, L33F, L89V | I13V, I15V, K20T, M36I, N37S, R41K, L63P, A71V, G73D, I93L |
| >1134-30326| codons 4-99 TLWQRPFVTVKVGGQLTEALLDTGADDTIFEEISLPGKWKPKIVGGIGGFMKVRQYDQIP IEICGHKVIDTVLVGPTPVNVIGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | V75L | K43E, S68G, K102Q, V118I, K122E, T200TI, H208HY, R211RK |
| >1134-30326| codons 38-247 CTELEEEGKISKIGPENPYNTPVFAIKKKDGTKWRKLLDFRELNKRTQDFWEVQLGIPHP AGLKQKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRIKIEELRQYLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |