Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1841 | 1841-30728 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, T215F | Y181C, G190S | K43E, K101Q, K122E, K166R, T200A, E203D, Q207A, H208Y, R211K, H221Y |
| >1841-30728| codons 40-247 EMEEEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAG LQKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAI FQSSMTRILEPFRKQNPDIVICQYMDDLYVSSDLEIGQHRAKIDELRAYLLKWGFFTPDK KYQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LV, E35D, M36I, N37E, R41K, I62IV, L63P, K70R, V77I |
| >1841-30728| codons 4-99 TLWQRPVVTIKIGGQLKEALLDTGADDTVLEDIELPGKWKPKMIGGIGGFIKVRQYDQVP IEICGHRAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |