Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1928 | 1928-30818 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54L, I84V, L90M | L33LF | L10I, N37NS, R41K, F53Y, I62V, L63P, I64V, H69Q, V77I, Q92R, I93M, C95F |
| >1928-30818| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMSLPGKWKPKIIGGIGGYLKVRQYDQVP VEICGQKAIGTVLIGPTPVNVIGRNLMTRMGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MV | K103N | R83K, K122P, I135T, D177E, T200IM, Q207A, R211RK |
| >1928-30818| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRMKIEELRAHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |