<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1366 1366-30821 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67HN, K70R, M184V, T215F K219Q     T39A, K43E, V60I, S68SN, T69TN, I135V, S162Y, D177G, V179I, T200A, Q207A, H208Y, R211K, K223Q, L228H, V245Q  
>1366-30821| codons 38-247
CAELEEEGKISKIGPENPYNTPIFAIKKKNNNRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRKQNPGIIIYQYVDDLYVGSDLEIGQHRAKIEELRAYLLKWGFFTP
DQKHQQEPPFHWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46IL, I54V, V82S L24I, K43T, F53FL L10IV, L19I, K20R, E35D, M36I, N37NS, R41K, K55KR, D60E, L63P, I64IMV, A71V, V77I, I93L  
>1366-30821| codons 4-99
TLWQRPVVTIKIGGQIREALIDTGADDTVLEDISLPGKWTPKLIGGIGGLVRVRQYEQIP
VEICGHKVIGTVLIGPTPSNIIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006