Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1809 | 1809-30429 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, I84IV | L10F, L24I, L33LF, K43T | M36MI, N37S, R41K, K55R, I62IV, L63P, I64V, A71AT, T91S |
| >1809-30429| codons 4-99 TLWQRPFVTIKIGGQLKEALIDTGADDTVFEEISLPGKWTPKIIGGIGGFVRVRQYDQVP VEICGHKTIGTVLVGPTPANVIGRNLLSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184MIV | V75A, K219Q | V90VI, V118VI, K122E, D123E, S162Y, G196GR, T200A, E203K, Q207E, D218DE, V245E | K64*Y, K73IM |
| >1809-30429| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIYKKNSTRWRMLADFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIRQHRAKIKELREHLLRWGFTTP EQKHQKEPPFLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |