Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1979 | 1979-30514 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54A, V82A, L90LM | L10FV, K43T | I13V, I15V, K20T, E35D, M36I, R41K, I62V, L63P, I64V, A71V, T74S, V77I, I93L |
| >1979-30514| codons 4-99 TLWQRPVVTVKVGGQLTEALLDTGADDTVLEDINLPGKWTPKIIGGIGGFAKVRQYDQVP VEICGHKVIGSVLIGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | T39S, R83RK, A98S, K122P, I142V, Q174QR, D177E, G196E, Q207E, R211K, L228R, D237E |
| >1979-30514| codons 38-247 CSELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHP SGLKKKKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPEIVIYQYVDDLYVGSDLEIEQHRTKIEELREHLWKWGFYTP DKKHQKEPPFRWMGYELHPEKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |