Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2038 | 2038-30709 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75M, M184I, L210W, T215Y | D67G, K70T, K219N | Y181C, G190S | K101N | T39A, E40F, K43KE, S68G, V118I, K122E, I135T, R211K, L228H, V245T |
| >2038-30709| codons 38-247 CAFLEEEGKISKIGPENPYNTPVFAIKKKGGTTWRKLMDFRELNKRTQDFWEVQLGIPHP AGLNKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYIDDLYVSSDLEIGQHRTKIEELRQHLWKWGFYTP DNKHQKEPPFHWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I50V, I54V, V82A, L90M | L10FV, V11VI, K43T, G73S, L89V | K14R, I15V, G16A, K20I, M36I, Q61QH, I62IV, L63P, A71V, I72IM, I85V | L19LHQ |
| >2038-30709| codons 4-99 TLWQRPVITIRVAGQQIEALLDTGADDTVLEEINLPGRWTPKIIGGVGGFVKVRQYDHVP IEICGHKVMSTVLVGPTPANIVGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |