<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1803 1803-30515 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74V, V75T, L210LW, T215F K219E L100I, K103N, M230L   T39A, K102R, I142T, E169D, V179VI, G196GE, T200A, I202V, D218DE, L228H, Q242QH P140PT
>1803-30515| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKVTDFRELNKRTQDFWEVQLGIPHP
AGIKRNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETTGTRYQYNVLPQGWKGSP
AIFQSSMTKILDPFRKQNPDIIIYQYMDDLYVGSDLEIEQHRAKVEELRQHLWRWGFFTP
EEKHQKEPPFHWLGYELHPDKWTVHPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82S L24I, Q58E L10I, K20R, E35D, M36I, N37D, R57K, L63P, I64V, A71AITV, I93L  
>1803-30515| codons 4-99
TLWQRPIVTIKIGGQLREALIDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVKEYDQIP
VEICGHKVIGTVLVGPTPSNIIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006