Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1803 | 1803-30515 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, V75T, L210LW, T215F | K219E | L100I, K103N, M230L | T39A, K102R, I142T, E169D, V179VI, G196GE, T200A, I202V, D218DE, L228H, Q242QH | P140PT |
| >1803-30515| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKVTDFRELNKRTQDFWEVQLGIPHP AGIKRNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETTGTRYQYNVLPQGWKGSP AIFQSSMTKILDPFRKQNPDIIIYQYMDDLYVGSDLEIEQHRAKVEELRQHLWRWGFFTP EEKHQKEPPFHWLGYELHPDKWTVHPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I54V, V82S | L24I, Q58E | L10I, K20R, E35D, M36I, N37D, R57K, L63P, I64V, A71AITV, I93L |
| >1803-30515| codons 4-99 TLWQRPIVTIKIGGQLREALIDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVKEYDQIP VEICGHKVIGTVLVGPTPSNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |