<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1313 1313-30513 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L210W, T215Y V75M, K219N L100I, K103N   E44ED, V60I, K64KR, V90VI, V118I, K122E, I135T, K173E, E203ED, R211K, K223T, L228R  
>1313-30513| codons 38-247
CTELEKDGKISKIGPENPYNTPIFAIRKKNSDKWRKLMDFRELNKRTQDFWEIQLGIPHP
AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFREQNPDIVIYQYMDDLYVGSDLEIGQHRTKIDELRQHLWKWGFYTP
DNKHQTEPPFRWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46L, I54L, I84V, L90M L33F, K43T L10V, I13V, E21EQ, E34K, D60E, L63PS, H69HY, T74TA, V77VI, L89F  
>1313-30513| codons 4-99
TLWQRPVVTVKIGGQLKQALLDTGADDTIFKEMNLPGRWTPKLIGGIGGFLKVRQYEQIS
IEICGYKAIGAVLIGPTPVNVIGRNFMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006