Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1313 | 1313-30513 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46L, I54L, I84V, L90M | L33F, K43T | L10V, I13V, E21EQ, E34K, D60E, L63PS, H69HY, T74TA, V77VI, L89F |
| >1313-30513| codons 4-99 TLWQRPVVTVKIGGQLKQALLDTGADDTIFKEMNLPGRWTPKLIGGIGGFLKVRQYEQIS IEICGYKAIGAVLIGPTPVNVIGRNFMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, L210W, T215Y | K219N | L100I, K103N | E44ED, V60I, K64KR, V90VI, V118I, K122E, I135T, K173E, E203ED, R211K, K223T, L228R |
| >1313-30513| codons 38-247 CTELEKDGKISKIGPENPYNTPIFAIRKKNSDKWRKLMDFRELNKRTQDFWEIQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFREQNPDIVIYQYMDDLYVGSDLEIGQHRTKIDELRQHLWKWGFYTP DNKHQTEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |