Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1007 | 1007-30519 | U.S. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | F227L | T39S, E44D, V111I, V118I, K122E, D123N, K173A, Q174K, D177E, I178L, T200A, E203K, Q207E, H208Y, R211K, K223E, V245Q |
| >1007-30519| codons 38-247 CSELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDIGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRAKNPELVIYQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTP DKKHQEEPPLLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54IV, V82A, L90M | L33F, K43KT | L10I, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93L |
| >1007-30519| codons 4-99 TLWQRPIVTIKVGGQTREALLDTGADDTVFEDINLPGKWTPKLIGGIGGFVKVRQYDEVP IEICGKKAIGSVLVGPTPANIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |