<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-4023 4023-30529 Australia 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, V75T, L210LW, T215FY K219N K103KN, Y181C, G190A V108I E44ED, K122E, D123E, I135V, N175H, D177E, G196E, T200A, K201I, E203D, E204Q, Q207QE, H208Y, R211K, H221Y  
>4023-30529| codons 38-247
CTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKITDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTILDVGDAYFSVPLDEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQHPEIVICQYMDDLYVASDLEIEQHRAIIDQLREYLWKWGFYTP
DNKYQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V L89V L10I, V11VL, I13V, K20IM, L33L_L, M36I, R41RK, K43KR, D60E, I62V, L63P, A71V, Q92K  
>4023-30529| codons 4-99
TLWQRPILTVKIGGQLMEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFVKVRQYEQVP
IEICGHKVIGTVLVGPTPANVIGRNVLTKIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006