<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA161451 BAA161451 Singapore 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI 274

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, V75M, M184V, T215F K219W     E6D, V35T, E36D, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, Q207A, R211K, K238R, V245EK, T286A, E291D, V292I, I293V, E312T, P321S, I326V, I329V, G335D, M357R, G359S, K366R, A371V, T386I, K390R, K395R, E399D A288KR
>BAA161451| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTDICKEMEEEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI
YQYVDDLYVGSDLEIEQHRTKIEELRAHLLKWGFFTPDWKHQKEPPFLWMGYELHPDRWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKRLTDIVPLTEEAE
LELAENREILKTPVHGVYYDSSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVRQLTEVVQKIATESIVIWGKIPKFRLPIQRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15V, E35D, M36I, N37D, R41K, H69K, L89M  
>BAA161451| codons 1-99
PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005