Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BAA161447 | BAA161447 | Singapore | 2003 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 74 |
| 2 | 3TC+AZT+NVP | 61 |
| 3 | 3TC+AZT+EFV | 117 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215F | K101E, Y188L | E6D, E28K, K32E, V35I, T39E, V60I, V90I, V106L, V118I, K122E, D123S, I135T, R172K, K173I, Q174K, D177E, I178L, V189I, G196E, E203K, Q207A, R211N, K223KQ, K238R, V245E, K275R, T286A, E291D, I293V, E312T, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, A376C, K390R, K395R |
| >BAA161447| codons 1-399 PISPIDTVPVKLKPGMDGPKVKQWPLTKEKIEALIEICEELEKEGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSLTVLDVGDAYFSIPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPELVI YQYMDDLLIGSDLEIEQHRTKIKELRAHLWNWGFFTPDKKHQQEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIRVKQLCKLLRGAKALTDVVPLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKICTESIVIWGKTPKFRLPIQRETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, E35D, M36I, R41K, H69K, V82I, L89M |
| >BAA161447| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hsu, LY | Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. | JAIDS, 2005 |