<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA161447 BAA161447 Singapore 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI 74
2 3TC+AZT+NVP 61
3 3TC+AZT+EFV 117

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, E35D, M36I, R41K, H69K, V82I, L89M  
>BAA161447| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L210W, T215F   K101E, Y188L   E6D, E28K, K32E, V35I, T39E, V60I, V90I, V106L, V118I, K122E, D123S, I135T, R172K, K173I, Q174K, D177E, I178L, V189I, G196E, E203K, Q207A, R211N, K223KQ, K238R, V245E, K275R, T286A, E291D, I293V, E312T, I326IV, I329V, G335D, M357K, G359S, K366R, A371V, A376C, K390R, K395R  
>BAA161447| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTKEKIEALIEICEELEKEGKISKIGPENPYNTPI
FAIKKKNSDKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSLTVLDVGDAYFSIPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPELVI
YQYMDDLLIGSDLEIEQHRTKIKELRAHLWNWGFFTPDKKHQQEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIRVKQLCKLLRGAKALTDVVPLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLTEVVQKICTESIVIWGKTPKFRLPIQRETWE

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005