Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BAA161440 | BAA161440 | Singapore | 2003 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 9 |
| 2 | 3TC+AZT+EFV | 65 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215F | Y188L | A98G, Y318F | E6D, K11T, V35T, E36A, T39K, K43E, K122E, D123S, I135L, K173T, Q174K, D177E, V179I, G196E, Q207A, R211S, V245K, E291D, V292I, I293V, E312T, I326V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395R |
| >BAA161440| codons 1-399 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTAICKELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIII YQYVDDLLVGSDLEIEQHRTKIEELRAHLWSWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKTPVHGVFYDPSKDLVAEIQKQGQDQWTYQIFQEPFKNLKTGKYARKRSA HTNDVRQLAEVVQKIATESIVIWGKTPKFRLPIQRETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, R41K, D60E, H69K, L89M, I93L |
| >BAA161440| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Hsu, LY | Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. | JAIDS, 2005 |