Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BAA161436 | BAA161436 | Singapore | 2003 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI | 52 |
| 2 | D4T+DDI+RTV+SQV | 26 |
| 3 | 3TC+AZT+NVP | 22 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, K70N, V75I | K101E, G190A | E6D, K11T, I31L, V35T, T39K, K43E, S68G, K122E, D123S, I135T, T139A, Q174R, D177E, I178M, T200R, Q207A, R211S, K238R, V245E, V276I, L283I, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T386I, K390R |
| >BAA161436| codons 1-399 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKLKALTEICKEMEEEGKISKIGPENPYNTPV FVIKKKDGTNWRKLIDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNEAPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKRNPEMVI YQYVDDLYVASDLEIGQHRRKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLIRGAKALTDIVPLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIATESIVIWGKIPKFRLPIQKETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | L10I, I13V, R41K, I62V, L63I, H69K, K70R, V82I, L89M |
| >BAA161436| codons 1-98 PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGFIKVRQYD QVIIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLN |
References
| Author | Title | Citation |
| Hsu, LY | Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. | JAIDS, 2005 |