<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA161430 BAA161430 Singapore 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV 96
2 3TC+AZT+IDV 31
3 3TC+AZT+SQV 57

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A F53L L10I, I13V, L19LV, K20R, E35D, M36I, N37D, R41K, I62V, L63LP, H69K, A71T, T74S, L89I  
>BAA161430| codons 1-99
PQITLWQRPIVTVKIGGQVREALLDTGADDTVLEDIDLPGKWKPKMIVGIGGLVKVRQYD
QVPIEICGKKTIGSVLVGPTPANIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, L74V   K101E, Y181C, G190A   E6D, K11T, K20R, V35T, T39K, K43E, K122E, D123NS, R172K, K173I, Q174KR, D177E, I178M, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, K311N, E312T, D324E, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R  
>BAA161430| codons 1-399
PISPIDTVPVTLKPGMDGPRVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIRNPEMVI
CQYMDDLYVASDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILNTPVHGVYYDPSKELVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQKETWE

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005