<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA161429 BAA161429 Singapore 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 109
2 IDV+RTV 78
3 D4T+DDI+EFV 96

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, K20R, E35D, M36I, R41K, H69K, I72V, L89M  
>BAA161429| codons 1-99
PQITLWQRPVVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KE, Q151M V75IT V106M, G190A V179D E6N, K11T, K20R, A33V, V35T, T39K, E40EK, K43E, S68SG, K122E, D123S, K173A, Q174K, D177E, Q207A, L210F, R211S, F214L, V245E, A272P, E291D, V292I, I293V, P294PT, E312T, I326V, I329V, Q334E, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395KR  
>BAA161429| codons 1-399
PISPINTVPVTLKPGMDGPRVKQWPLTEEKIKVLTEICKKMEEEGKISKIGPENPYNTPV
FAIKKKNGTEWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRAKNPEIDI
YQYMDDLYVASDLEIGQHRTKIEELRAHLFSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVTLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGEDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLAEVVQKIATESIVIWGKTPKFRLPIQRETWE

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005