<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA157684 BAA157684 Singapore 2002 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 22

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       P4X, E6ED, K11T, I31L, V35T, T39K, K43E, K66KR, W88S, V111I, V118I, K122E, D123N, K173I, Q174K, D177E, I178L, T200A, Q207A, R211GS, F214L, K238R, V245E, K275Q, K277R, T286A, E291D, I293V, E297A, E312AT, I326V, I329V, G335D, F346FY, R356RK, M357K, G359S, K366R, A371V, K390R  
>BAA157684| codons 1-399
PISXIDTVPVTLKPGMDGPKVKQWPLTEEKLKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKRDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKKKSVTVLDIGDAYFSIPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDVVPLTAEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPYKNLKTGKYAKKRSA
HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, G16GE, E35D, M36I, R41K, H69K, L89M, L97I  
>BAA157684| codons 1-99
PQITLWQRPIVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTINF

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005