Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BAA148375 | BAA148375 | Singapore | 2002 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T | 44 |
| 2 | AZT+DDI | 35 |
| 3 | RTV+SQV | 4 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | E6D, T7TA, K11T, V35T, T39K, K43E, E44A, K122E, D123S, K173I, Q174K, D177E, I178M, T200A, Q207K, R211S, V245E, A272P, E291D, V292I, I293V, E297A, E312A, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, K390R, K395R | E89EG |
| >BAA148375| codons 1-399 PISPIDAVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKELEEAGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWGVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTAEAE LELAENREILKAPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLTEVVQKIVTESIVIWGKTPKFRLPIQRETWE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, H69K, L89M |
| >BAA148375| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Hsu, LY | Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. | JAIDS, 2005 |