<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA148362 BAA148362 Singapore 2002 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 65
2 D4T+DDI 204

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W T215S K101E, Y181C A98G E6D, V35T, T39K, K43E, V60I, S68G, K122E, D123S, I135KR, K166R, K173I, Q174K, D177E, G196E, T200A, R206K, Q207A, R211S, V245E, A272P, T286A, I293V, E297K, E312A, I326V, I329V, G335D, P345Q, M357K, G359S, K366R, A371V, K390R  
>BAA148362| codons 1-399
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEIVI
CQYMDDLYVGSDLEIEQHRAKIEELKAHLWSWGFSTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTKEAE
LELAENREILKAPVHGVYYDPSKDLVAEVQKQGQDQWTYQIYQEQFKNLKTGKYARKRSA
HTNDVRQLTEVVQKIATESIVIWGKTPKFRLPIQKETWE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V L33F, N83D, L89V L10I, I13V, E35D, M36IL, N37D, K43R, R57K, L63LP, H69K, A71V  
>BAA148362| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVFEDLDLPGRWRPKMIGGIGGFIKVKQYD
QIPIEICGKKVIGTVLVGPTPVDVIGRNVLTQIGCTLNF

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005