<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA148361 BAA148361 Singapore 2002 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T 104
2 DDI 22

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, E35D, M36I, R41K, H69K, K70KR, I72V, L89M  
>BAA148361| codons 1-99
PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y       E6D, K11T, K20R, V35T, T39K, K43E, V60I, S68G, V106I, K122E, D123N, I135T, K173I, Q174K, D177E, I178L, T200A, Q207A, R211S, I244V, V245E, A272P, T286TA, E291D, V292I, I293V, P294Q, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, K390R, K395R  
>BAA148361| codons 1-399
PISPIDTVPVTLKPGMDGPRVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPVELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVQLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQDQWTYQIFQEPFKNLKTGKYARKRSA
HTNDVRQLAEVVQKIATESIVIWGKTPKFRLPIQRETWE

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005