<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BAA148360 BAA148360 Singapore 2002 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT 70
2 3TC+D4T 165

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, M184V, T215Y       E6D, K11KT, V35T, T39K, K43E, K122E, D123S, I135IV, S162SDGN, K173I, Q174K, D177E, Q207A, R211S, K238KR, V245E, K277R, T286A, I293V, E312T, V317VA, I326LV, I329V, G335D, F346FY, M357Q, G359S, K366KR, A371V, I382IV, K390R, K395R, E399ED  
>BAA148360| codons 1-399
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPV
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRIKNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELRAHLLSWGFYTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKTPVHGAYYDPSKDLVAEVQKQGQDQWTYQIYQEPYKNLKTGKYARQRSA
HTNDVRQLTEVVQKIATESIVVWGKTPKFRLPIQRETWD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16A, E35D, M36I, R41K, L63P, H69K, I72V, L89M, I93L  
>BAA148360| codons 1-99
PQITLWQRPLVTIKIAGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAVGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Hsu, LY Characterization of mutations in CRF01_AE virus isolates from antiretroviral treatment naive and experienced patients in Singapore. JAIDS, 2005