<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1958 04MYKL1958 Malaysia 2004 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 3TC+AZT+EFV+IDV+RTV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L76V   I13V, K14R, K20I, E35N, M36I, R41K, K55R, R57K, L63P, H69K, K70R, I72V, L89M  
>04MYKL1958| codons 1-95
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLENINLPGKWKPKIIGGIGGFIRVKQYD
QIPIEICGKRAVGTVVVGPTPVNIIGRNMLTQIGC

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V   L100I, K103N P225H V35T, T39K, K43E, K122E, D123S, K173I, Q174K, D177E, Q207A, R211S, V245E  
>04MYKL1958| codons 20-247
KVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRE
LNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVIYQYMDDLYVGSDLEIGQHR
TKIEELRAHLLSWGFTTPDKKHQKEHPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006