<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1822 04MYKL1822 Malaysia 2004 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 EFV+IDV+RTV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T215F K219E K101E, Y181C, G190S   L34I, V35T, T39E, V60I, W88C, K122E, D123S, S162Y, K173I, Q174K, D177E, I178L, R206K, Q207A, R211S, V245E  
>04MYKL1822| codons 20-247
KVKQWPLTEEKIKAITEICEEMEKEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRE
LNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNET
PGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRIKNPELVICQYMDDLYVSSDLEIGQHR
TKIEELKAHLLSWGFFTPDEKHQKEPPFLWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V L89V L10I, I13A, K14R, K20I, E35D, M36I, R41K, K55R, I66F, H69K, A71T  
>04MYKL1822| codons 1-95
PQITLWQRPIVTARIGGQLIEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFIRVRQYD
QILIEFCGKKTIGTVLVGPTPVNVIGRNVLTQIGC

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006