<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1855 04MYKL1855 Malaysia 2004 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82F L33I, L89V L10I, I13V, Q18H, A22V, E35D, M36I, N37D, H69K, A71V, I93M  
>04MYKL1855| codons 1-95
PQITLWQRPIVTVKIGGHLKEVLLDTGADDTVIEDIDLPGRWKPKMIGGIGGFVKVRQYD
QILIEICGKKVIGTVLVGPTPFNIIGRNVLTQMGC

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y   Y188L   V35T, T39K, K43E, K122E, D123S, S162C, I202V, V245E  
>04MYKL1855| codons 20-247
KVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRE
LNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNET
PGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVIYQYVDDLLVGSDLEIGQHR
TKVEELRQHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006