<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1570 03MYKL1570 Malaysia 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 113

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, M36I, N37D, R41K, H69K, V82I, L89M  
>03MYKL1570| codons 1-95
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGC

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215F   Y188L V179E V35T, T39K, K43E, E44D, K64R, V111I, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V189I, G196E, T200A, Q207A, H208Y, R211S, W212C, K238R, V245E  
>03MYKL1570| codons 20-247
KVKQWPLTEEKIKALTEICKELEEDGKISKIGPENPYNTPVFAIRKKNSTKWRKLVDFRE
LNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYFSIPLDESFRKYTAFTIPSINNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMEIYQYVDDLLIGSDLEIEQHR
AKIEELRAYLWSCGFFTPDKKHQKEPPFLWMGYELHPDRWTVQPIELP

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006