<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1518 03MYKL1518.1 Malaysia 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV 31

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y   Y188L A98G V35T, T39K, K43E, E44D, V106I, V118I, K122E, D123S, I135V, R172K, K173I, Q174K, D177E, I178M, T200I, I202V, Q207A, R211N, K238R, V245E  
>03MYKL1518.1| codons 20-247
KVKQWPLTEEKIKALTEICKELEEDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRE
LNKRTQDFWEVQLGIPHPGGLKKKKSITVLDVGDAYFSIPLDESFRKYTAFTIPSVNNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPEMVIYQYMDDLLVGSDLEIGQHR
IKVEELRAHLWNWGFYTPDKKHQKEPPFLWMGYELHPDRWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M  
>03MYKL1518.1| codons 1-95
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGC

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006