<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MYKL1356 03MYKL1356.1 Malaysia 2003 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 D4T+DDI+EFV 96

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20R, M36I, R41K, H69K, L89M  
>03MYKL1356.1| codons 1-95
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGC

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, L210W, T215F D67G L100I, K103N   V35T, T39K, K43E, V60I, S68G, V118I, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, T200E, Q207A, R211S, K238R, V245E  
>03MYKL1356.1| codons 20-247
KVKQWPLTEEKIKALTEICKELEEEGKISKIGPENPYNTPIFAIKKKGGTKWRKVVDFRE
LNKRTQDFWEVQLGIPHPAGIKKNKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSTNNET
PGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMIIYQYMDDLYVGSDLEIGQHR
EKIEELRAHLWSWGFFTPDKKHQKEPPFLWMGYELHPDRWTVQPIELP

References
Author Title Citation
Tee, KK Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia. Med Microbiol Immunol, 2006