<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CK22-57 03CM2-57 Cameroon 2003 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV 30

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    K103N   V35T, E36D, T39V, V60I, K104R, K122E, D123S, I135V, S162A, K173V, Q174K, D177E, I178M, T200A, Q207E, R211T, V245Q, T286A, E291D, V292I, I293V, P294T, S322A, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, K390R, A400T, T403Q, E432D  
>03CM2-57| codons 1-432
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICVEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRVKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLTWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVRQLTEVVQKVATESIVIWGKTPKFRLPIQKETWETWWQEYWQATWIPEWEFVNTP
PLVKLWYQLEKD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20I, E34T, M36I, P39V, R41K, I62V, H69K, L89M  
>03CM2-57| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLTEINLVGKWKPKMIGGIGGFIKVRQYD
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Laurent, C Antiretroviral drug resistance and routine therapy, Cameroon. Emerg Infect Dis, 2006