<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CK2-76 02CM-76 Cameroon 2002 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 3TC+EFV+D4T 43

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   K103N, M230L   V35T, K122E, D123E, A158S, K173A, Q174K, D177E, I178L, Q207E, P243A, V245Q, E248D, D250S, A272P, K275R, L279M, T286A, E291D, I293V, E297A, D324E, P345L, F346H, R356K, M357S, G359S, A371V, T386V, K390R, A400I, K431T, E432D  
>02CM-76| codons 1-438
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAKNPELVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFYTPDKKHQKEPPFLWLGYELHPDKWT
VQAIQLPDKSSWTVNDIQKLVGKLNWASQIYPGIRVKQMCKLLRGAKALTDVVPLTAEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQGQWTYQIYQELHKNLKTGKYAKSRSA
HTNDVKQLTEVVQKIATESIVIWGKVPKFRLPIQKETWEIWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETDPIVGAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, I15V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, I62V, L63S, H69Q, L89M  
>02CM-76| codons 1-99
PQITLWQRPIVTVKVEGQLREALLDTGADDTVLEDINLSGKWKPRMIGGIGGFIKVRQYD
QVSIEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Laurent, C Antiretroviral drug resistance and routine therapy, Cameroon. Emerg Infect Dis, 2006