<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Fj065 Fj065 China 2004 HIV1 CRF01_AE PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, A23V, V31I, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, R224Q, L234I S283G
>Fj065| codons 1-288
FLDGIDKAQEEHERYHSNWRTMVSDFNLPPIIAKEIVANCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVRQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKQITKIQNFQVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, M36I, N37D, R41K, D60E, H69K, L89M, I93L  
>Fj065| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  V75L     E6D, K11T, K20R, V35T, T39K, V111I, K122E, D123N, K166R, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E297A, A304E, E312T, I329V, G335D, E344A, P345Q, M357K, R358S, G359S, K366R, A371V, A376V, K390R, K395R, T397V, A400T, E432D, I434L, N447S, D471E, Q480H, H483Y, L484S, L491S, K512R, L517I, S519N, Q524E, K527R, E529D, A534S, V536A, A554T Y232C
>Fj065| codons 1-560
PISPIDTVPVTLKPGMDGPRVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLLDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDIGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEMII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGCELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDIVPLTAEAE
LELEENREILKTPVHGVYYDPSKDLIAEVQKQGQDQWTYQIYQAQFKNLKTGKYARKSSA
HTNDVRQLTEVVQKIVTESIVIWGKTPKFRLPIQREVWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPLVGAETFYVDGAASRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIYSALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEELIRKDKVYLSWAPAHK
GIGGNEQVDKLVSTGIRKVL

References
Author Title Citation
Hai-Long, H Genetic characterization of CRF01_AE full-length human immunodeficiency virus type 1 sequences from Fujian, China. ARHR, 2007