<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Fj057 Fj057 China 2004 HIV1 CRF01_AE PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V32I, I72V, K111R, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, T218S, L234I, S255C  
>Fj057| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRVIHTDNGSN
FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQISKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNCDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, E35D, M36I, R41K, H69K, L89M  
>Fj057| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11A, V35T, T39K, K122E, D123N, I135T, I142V, K166R, K173I, Q174K, D177E, I202V, Q207K, R211S, K238R, V245E, V276I, T286A, E291D, I293V, E312N, I326V, A327V, I329V, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, V381I, K390R, K395R, A400T, E432D, L452V, D471E, H483Q, L491S, K512R, L517V, Q524E, A534S, I542V, A554S  
>Fj057| codons 1-560
PISPIDTVPVALKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEIVI
YQYMDDLYVGSDLEIGQHRTKVEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKIKQLCKLLRGAKALTDVVPLTEEAE
LELAENREILKNPVHGVYYDPSKDLVVEVQKQGQDQWTYQIFQEPFKNLKTGKYARKRSA
HTNDVRQLAEVVQKIATESIIIWGKTPKFRLPIQRETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKVGKAGYVTDRGRQKVVSLTETTNQKTELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEVVSQIIEELIKKEKVYLSWVPAHK
GVGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Hai-Long, H Genetic characterization of CRF01_AE full-length human immunodeficiency virus type 1 sequences from Fujian, China. ARHR, 2007