Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 143P1 | 143P1W88 | U.S. | 1993 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 88 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | D121H, K122E, I135T, S162C, D177E, R211K |
| >143P1W88| codons 26-242 LTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQ DFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQ YNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRTKIEEL RQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQ |
References
| Author | Title | Citation |
| Winters, MA | Human immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 years. | AAC, 1997 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |