Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JKC-VI1126 | VI1126 | DRC | 1994 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, V31I, Y99F, L101I, T112I, T122I, T124A, K136Q, V165I, T206S, K211R, E212A, L234I, D256E | P142S, S283G |
| >VI1126| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAFFILKLAGRWPVKIIHTDNGSN FISATVKAACWWAGIQQEFGISYNPQSQGVVESMNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIASDIQTRALQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, K20R, E35D, M36I, R41K, I62V, L63V, I64M, H69Q, L89M |
| >VI1126| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVVMEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219E | V35T, T39L, V60I, T69N, K122P, D123E, I135V, I142V, S162Y, K173T, Q174K, D177E, I178M, Q207E, V245Q, E248D, D250E, S251D, A272P, L283I, T286A, A288T, E291D, V292I, I293V, E297A, F346Y, G359S, S379G, K390R, A400T, K431T, E432D, V435A, L452K, K454R, R461K, D471E, A481T, H483Y, L491S, L503I, S519N, K527Q, E529D, K530Q, V531I, A534S, A554S | W266R |
| >VI1126| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPEFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKEDWTVNDIQKLVGKLNRASQIYPGIKVKQLCKLIRGAKTLTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPYKNLKTGKYARMRSA HTNDVKQLTEAVQKIATEGIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLETDPIAGAETFYVDGAANRETKKGRAGYVTDKGRQKVVSLTETTNQKTELQ TIYLALQDSGSEVNIVTDSQYAIGIIQAQPDKSESELVNQIIEQLIQKDQIYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Carr, JK | Direct Genbank submission: HIV-1 isolates from the Democratic Republic of the Congo and from Gabon. | Direct Genbank Submission, 1999 |