Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JKC-SE6954 | VI6954 | Sweden | 1993 | HIV1 | D | PBMC | Genomic |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, M50L, I72V, K111R, T112V, I113V, T125A, K173R, V201I, K215R, L234I, D256E, A265V |
| >VI6954| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEALHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRVVHTDNGSN FTSTAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLRTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQRQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36I, R41K, H69Y, T96A |
| >VI6954| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCALNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11Q, V35T, S48A, K49R, V60I, D121Y, K122E, D177E, I178M, T200I, Q207G, R211K, V245T, D250E, A272P, K277R, L282C, L283I, T286A, I293V, G335D, P345Q, F346Y, R356K, M357V, A360T, V365I, E370A, T377Q, S379C, K390R, A400T, E432D, I434M, S468P, D471E, Q480H, L491S, A534S, K540R, A554N, V559I |
| >VI6954| codons 1-560 PISPIETVPVQLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIARIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEQYKNLKTGKYAKVRGT HTNDIKQLTAAVQKIAQECIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKDPMVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVPLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLSWVPAHR GIGGNEQVDKLVSNGIRKIL |
References
| Author | Title | Citation |
| Wilbe, K | Characterization of novel recombinant HIV-1 genomes using the branching index. | Virology, 2003 |
| Carr, JK | Direct Genbank submission: HIV-1 isolates from the Democratic Republic of the Congo and from Gabon. | Direct Genbank Submission, 1999 |