Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 90CR102 | 90CR402 | CAR | 1990 | HIV1 | A | PBMC | Genomic |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E11D, K14R, V31I, I72V, K111R, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, G193E, V201I, E212A, L234I | S283G, D286N |
| >90CR402| codons 1-288 FLDGIDKAQEDHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRVIHTDNGSN FTSAAVKAACWWANVQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGEYSAGERIIDIIATDIQTKALQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQNED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, R41K, H69K, L89M |
| >90CR402| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, K11T, V35T, T39K, K43E, K122E, D123G, I142V, K173A, Q174R, D177E, I202V, E204D, Q207A, R211S, K238R, K277R, T286A, E291D, V292I, I293V, P294T, E312T, I326V, G335D, M357K, G359S, K366R, T369A, A371V, I375V, K390R, K395R, A400T, T403M, E432D, V435M, N447S, L452Q, D471E, Q480H, L491P, K512R, E516D, L517I, S519N, Q524K, K527E, A534S, A554S |
| >90CR402| codons 1-560 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI YQYMDDLYVGSDLEIGQHRTKVEDLRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVRQLAEVVQKVATESIVIWGKTPKFRLPIQRETWETWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIMGAETFYVDGAASRETKQGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGPEVNIVTDSQYALGIIQAQPDRSESDIVNQIIEKLIEKEKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Gao, F | The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin. | J Virol, 1996 |