Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 92UG037 | 92UG037 | Uganda | 1992 | HIV1 | A | PBMC | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, V31I, I72V, I84V, T112V, I113V, T124A, T125A, G134N, I135V, D167E, V201I, T206S, I208L, N222K, L234I, A265V, R269K | Y226C, S283G |
| >92UG037| codons 1-288 FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYVEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWANVKQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDLQTKELQKQITKIQKFRVCYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIKDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E21K, E35D, M36I, R41K, R57K, H69K, L89M, Q92L |
| >92UG037| codons 1-99 PQITLWQRPLVTVKIGGQLKKALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTLIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6S, K20R, V21I, V35T, T39A, E40D, K43R, K46R, V60I, K122E, D123S, I135T, S162A, K173S, Q174K, Q207E, R211K, V245E, D250E, E291D, V292I, I293V, P294T, E312D, V317A, G335D, T338I, M357K, G359S, T369A, A371V, I375V, A376V, T377M, A400T, T403M, E404D, W410*, E432D, V435A, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S |
| >92UG037| codons 1-560 PISPISTVPVKLKPGMDGPRIKQWPLTEEKIKALTEICADMEREGRISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRSKNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVTLTEEAE LELAENREILKDPVHGAYYDPSKDLIAEIQKQGQDQWIYQIYQEPFKNLKTGKYARKRSA HTNDVKQLAEVVQKVVMESIVIWGKTPKFKLPIQKETWETWWMDYWQAT*IPEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Gao, F | Molecular cloning and analysis of functional envelope genes from human immunodeficiency virus type 1 sequence subtypes A through G. The WHO and NIAID networks for HIV isolation and characterization. | J Virol, 1996 |
| Gao, F | The heterosexual human immunodeficiency virus type 1 epidemic in Thailand is caused by an intersubtype (A/E) recombinant of African origin. | J Virol, 1996 |