Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99ZATM10 | 99ZATM10 | South Africa | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24N, D25E, M50I, I84M, F100Y, L101I, T112V, T125A, K136Q, V201I, I203M, K215N, L234I, V260I, D278A | S283G |
| >99ZATM10| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMANEFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYMEAEVIPAETGQETAYYILKLAGRWPVKVIHTDNGSN FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQNQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVIPRRKAKIIRDYGKQMAGADCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L |
| >99ZATM10| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123N, K173T, Q174R, T200A, Q207E, K238R, V245Q, S251N, A272P, K275R, Q278Y, T286A, E291D, V292I, I293V, E328D, G335D, R356K, G359T, T377M, T386I, K390R, E399G, V435I, L452I, V458I, R461K, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, V548I, A554S |
| >99ZATM10| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIQLPEKDNWTVNDIQKLVGKLNWASQIYPGIRVKYLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIADIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKIAMESIVIWGKIPKFRLPIQKETWGAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKIGKAGYITDKGRQKIVSLTETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQIDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Papathanasopoulos, MA | Full-length genome characterization of HIV type 1 subtype C isolates from two slow-progressing perinatally infected siblings in South Africa. | ARHR, 2003 |