Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RL42 | RL42 | China | 1998 | HIV1 | B | PBMC | Genomic |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| N155D | S17C, S119R, T124N, T125S, K211R, D229G, A265V |
| >RL42| codons 1-288 FLDGIDKAQEEHEKYHCNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGRN FTSNSVKAACWWAGIKQEFGIPYNPQSQGVVESMDKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTRELQKQITKIQNFRVYYRGSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, L63P, I93L |
| >RL42| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P236L | E6K, I135V, S162C, T200A, V245M, Q278E, P313S, Q334L, F346Y, V417I, P420S, V435E, G436E, D460N, R461K, S468T, H483Y, L491V, V548I | V90A |
| >RL42| codons 1-560 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEAQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHLDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKELCKLLRGTKALTEVIPLTEEAE LELAENREILKESVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPYKNLKTGKYARMRGA HTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFINTS PLVKLWYQLEKEPIEEAETFYVDGAANRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQ AIYLALQDSGVEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK GIGGNEQIDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Graf, M | Cloning and characterization of a virtually full-length HIV-1 genome from a subtype B'-Thai strain representing the most prevalent B-clade isolate in china. | ARHR, 1998 |