Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB2059 | MB2059 | Kenya | 1993 | HIV1 | D | PBMC | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S17N, M50L, I72V, T112V, I113V, T124A, T125A, V201I, T218I, L234I, D256E, A265V |
| >MB2059| codons 1-288 FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEALHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGSN FTSAAVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSEIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, I15V, G16X, M36I, R41K, I64V, H69R |
| >MB2059| codons 1-99 PQITLWQRPVVTVKVXGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGRKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K32R, V35T, E36D, K49R, V60I, D121Y, K122E, D123E, I159V, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, K275R, K277R, L282C, T286A, I293V, S322A, Q332L, G333R, G335E, Q336K, Y342F, P345Q, F346Y, R356K, A360T, I375V, T377Q, S379C, K390R, A400T, T403A, V435I, V458I, H483N, L491V, S519N, A534S, A554N, V559I |
| >MB2059| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIRALTDICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAVFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIRVRQLCKCLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKLRQEKWTYQIFQEQYKNLKTGKYAKMRGT HTNDVKQLTEAVQKVAQECIVIWGKTPKFRLPIQKETWETWWAEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYITDRGRQKVVSLTDTTNQKTELQ AINLALQDSGVEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK GIGGNEQVDKLVSNGIRKIL |
References
| Author | Title | Citation |
| Neilson, JR | Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, Kenya. | J Virol, 1999 |