Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Q23-17 | Q23-17 | Kenya | 1994 | HIV1 | A | PBMC | MC |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, A21T, V31I, I72V, L74V, T112I, I113V, T124A, T125A, G134N, K136Q, D167E, V201I, Q216H, L242F | S283G |
| >Q23-17| codons 1-288 FLDGIDKAQEEHERYHSNWRTMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVIVVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIVHTDNGSN FTSAAVKAACWWANIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKHITKIQNFRVYYRDSRDPLWKGPAK LFWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M |
| >Q23-17| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215I | V35T, V60I, D121H, K122E, D123E, I135T, I142V, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L, V245E, T286A, E291D, I293V, P294T, G335D, Y342F, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, K390R, E399D, A400T, T403M, E404D, P412L, E432D, V435A, R461K, D471E, Q480H, L491S, L517I, S519N, Q524K, K527E, E529D, A534S, A554S |
| >Q23-17| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGLITPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIFQEPFKNLKTGKYARKRSA HTNDVRQLAEVVQKVVMESIVIWGKTPKFRLPIQKETWDTWWMDYWQATWILEWEFVNTP PLVKLWYQLEKDPIAGAETFYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEKLIEKDKVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Neilson, JR | Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, Kenya. | J Virol, 1999 |