Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 97CDKFE4 | 97CDKFE4 | DRC | 1997 | HIV1 | A | PBMC | Genomic |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| K14R, S24Q, V31I, I72V, L101I, T112V, S119P, T124A, I135V, K136Q, K160R, V165I, V201I, T218I, L234I | S283C |
| >97CDKFE4| codons 1-288 FLDGIDKAQEEHERYHSNWRAMAQDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN FTSATVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKRIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVACRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20R, E35D, M36I, R41K, L63A, H69K, K70R, L89M, T91V, I93L |
| >97CDKFE4| codons 1-99 PQITLWQRPLVTVKIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIAIEICGKRAIGTVLVGPTPVNIIGRNMLVQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39G, K122E, T139S, A158S, K173S, Q174K, N175Y, D177E, I178M, T200A, Q207A, V245K, K281R, E291D, V292I, I293V, P294T, E297K, A304E, E312N, G335D, R356K, M357K, R358K, G359S, A360T, T377I, K390R, A400T, K431T, I434L, V435A, V466I, D471E, Q480H, H483Y, K512R, S519N, Q524K, K527E, K530R, A554S |
| >97CDKFE4| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICGEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNESPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRSKYPEMVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGTKALTDIVTLTKEAE LELEENREILKNPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKKST HTNDVKQLTEAVQKIAIESIVIWGKTPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP PLVKLWYQLETEPLAGAETFYVDGAANRETKLGKAGYVTDRGRQKIVSLTETTNQKTELH AIYLALQDSGLEVNIVTDSQYALGIIQAQPDRSESELVNQIIEKLIEKERVYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Gao, F | Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation. | ARHR, 2001 |